منابع مشابه
Bidirectional Gene Organization A Common Architectural Feature of the Human Genome
tion about each gene pair develops, some of these up-Bidirectional Gene Organization: stream gene candidates may change category or be determined not to encode protein.) A common feature of these bidirectional loci is the of the Human Genome presence of a CpG island between the genes (Figure 1A). In nearly all cases, a CpG island overlapped partially or entirely the first exon (or occasionally ...
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Gene families are considered as groups of homologous genes which they share very similar sequences and they may have identical functions. Members of gene families may be found in tandem repeats or interspersed through the genome. These sequences are copies of the ancestral genes which have underwent changes. The multiple copies of each gene in a family were constructed based on gene duplicati...
متن کاملGene Organization and Evolutionary Considerations
The sequence of a 8351-nucleotide mitochondrial DNA (mtDNA) fragment has been obtained extending the knowledge of the Drosophila melanogaster mitochondrial genome to 90% of its coding region. The sequence encodes seven polypeptides, 12 tRNAs and the 3' end of the 16s rRNA and CO I11 genes. The gene organization is strictly conserved with respect to the Drosophila yakuba mitochondrial genome, an...
متن کاملInference of Boolean networks under constraint on bidirectional gene relationships.
The coefficient of determination (CoD) has been used to infer Boolean networks (BNs) from steady-state data, in particular, to estimate the constituent BNs for a probabilistic BN. The advantage of the CoD method over design methods that emphasise graph topology or attractor structure is that the CoD produces a network based on strong predictive relationships between target genes and their predi...
متن کاملBidirectional Grammar and Bidirectional Optimization
The human language faculty is a bidirectional system, i.e. it can be used by processes of approximately equal computational complexity to understand and to generate utterances of a language. We assume the general framework of optimality theory and treat the language faculty as a constraint-based system where the very same constraints are uses both in comprehension and in generation. In the simp...
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ژورنال
عنوان ژورنال: Cell
سال: 2002
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(02)00758-4